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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RFC1 All Species: 9.39
Human Site: Y266 Identified Species: 18.79
UniProt: P35251 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P35251 NP_002904.3 1148 128255 Y266 S K A E K H K Y P H K V K T A
Chimpanzee Pan troglodytes XP_001140765 1148 128250 Y266 S K A E K H K Y L H K V K T A
Rhesus Macaque Macaca mulatta XP_001091287 1148 128475 Y266 N K A E K R K Y P H K V K T E
Dog Lupus familis XP_536259 1145 128125 K263 A N L S K A G K H K S P H K V
Cat Felis silvestris
Mouse Mus musculus P35601 1131 125967 K263 D D L S K A E K Q K S P N K A
Rat Rattus norvegicus NP_445999 1131 125770 A261 A K A E L S K A A K Q K S P A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512744 1233 136122 H349 A E K Q T H S H K G G R A R F
Chicken Gallus gallus NP_001006456 1147 128454 Q263 N V T E R Y K Q S Q R V K A A
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P35600 986 108596 E166 R A K N S S P E P P K P K S T
Honey Bee Apis mellifera XP_397246 911 103001 Q91 P K I S K Q L Q K K E A K S H
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_797949 906 99249 S86 T L V K Q T E S K T S K G P T
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P38630 861 94885 D41 I D L D T E S D Q E S T N K T
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 97.3 89.3 N.A. 82.4 81.3 N.A. 67.4 68.9 N.A. N.A. N.A. 39.9 36.2 N.A. 38
Protein Similarity: 100 99.6 98.5 93.7 N.A. 89.5 88.5 N.A. 77.2 79.6 N.A. N.A. N.A. 55.9 53.6 N.A. 52.2
P-Site Identity: 100 93.3 80 6.6 N.A. 13.3 33.3 N.A. 6.6 33.3 N.A. N.A. N.A. 20 20 N.A. 0
P-Site Similarity: 100 93.3 86.6 13.3 N.A. 20 46.6 N.A. 33.3 60 N.A. N.A. N.A. 26.6 33.3 N.A. 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. 30 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 46.3 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 0 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 6.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 25 9 34 0 0 17 0 9 9 0 0 9 9 9 42 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 9 17 0 9 0 0 0 9 0 0 0 0 0 0 0 % D
% Glu: 0 9 0 42 0 9 17 9 0 9 9 0 0 0 9 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 9 % F
% Gly: 0 0 0 0 0 0 9 0 0 9 9 0 9 0 0 % G
% His: 0 0 0 0 0 25 0 9 9 25 0 0 9 0 9 % H
% Ile: 9 0 9 0 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 42 17 9 50 0 42 17 25 34 34 17 50 25 0 % K
% Leu: 0 9 25 0 9 0 9 0 9 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 17 9 0 9 0 0 0 0 0 0 0 0 17 0 0 % N
% Pro: 9 0 0 0 0 0 9 0 25 9 0 25 0 17 0 % P
% Gln: 0 0 0 9 9 9 0 17 17 9 9 0 0 0 0 % Q
% Arg: 9 0 0 0 9 9 0 0 0 0 9 9 0 9 0 % R
% Ser: 17 0 0 25 9 17 17 9 9 0 34 0 9 17 0 % S
% Thr: 9 0 9 0 17 9 0 0 0 9 0 9 0 25 25 % T
% Val: 0 9 9 0 0 0 0 0 0 0 0 34 0 0 9 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 9 0 25 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _